Ask Our Doctors – Archive

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

19,771 Comments

  1. Is 500-1000pg/ml what you think is optimum for e2 prior to a 5 day transfer? Is the an optimum for p4? My failed transfer of 2 ACgH tested embryos which were 5aa and 4ab had the e2 within range but my lining was only 7.4mm. Do you think this was my problem? I only have one embryo left next time so I need to get it right. I was on oral 4mg oestrogen daily plus patches and progesterone suppositories 3 x 200mg prior to transfer and 6 x 200mg after. I am wondering if I should go to injection. I really need the next one to work. Thank you for your time

    • Perhaps we should talk~!

      Geoff Sher
      PH: 800-780-7437

  2. Hi again Dr.

    My hcg went from 930 to 7207 in 3 days. I am now 13 days past FET. However, progesterone went from 22 to 16.7. Is that ok? I am taking progesterone shots daily and endometrin 3 times daily.

    • The progesterone is still OK and that rapid rise in the hCG level could point to a multiple pregnancy or molar degeneration. Only time can tell!

      Geoff Sher

  3. I did IVF 6 months ago. I have autoimmune diseases, lowish AMH (1.3 at 34 yrs old) and poor egg quality. After birth control pills, I stimmed for 10 days on 100 units of follistim and 1 vial of menopur and added in orglautran halfway through, plus had a Lupron trigger. I had 19 follicles, 14 eggs, 8 mature, 6 blasts but only 1 PGS normal (hence the egg quality from autoimmune disease).

    Would like to do another round but my dr is suggesting a quick start without birth control pills, doubling my dose to get more eggs and hopefully more PGS normal ones.

    What are your thoughts about skipping birth control and doubling the dose?

    Also I’ve heard HGH can help egg quality … is this something to suggest to my doctor?

    Many thanks.

  4. Hi,

    My husband and I are using a gestational carrier. We have PGS tested embryos ( I have 13;22 translocation) I have had multiple miscarriages even on our PGS tested embryos. Our dr thought it would be best to use a surrogate since he cannot figure out what is wrong with me. I have also been to Mary Stephenson in Chicago and she cannot figure anything out either. So we moved on to using a gestational carrier. Our carrier completed a cycle in April which resulted in a chemical pregnancy. We did another cycle in May and she was pregnant again and it was another chemical. Her lining the first time was 11, the second time her lining was 9. Each FET cycle she has had low E2 levels. For example, she started her estrace orally on day 1 of her period. Her level was 50.1 on May 11. On May/17 her level was 222, on May 24 her level was 311. The transfer was on May 30. June 4 her E2 was 215, June 7 her E2 was 192. I’m wondering if her E2 levels are too low? The embryos were graded 6BB, and 5BB and PGS normal. Do you think her E2 level is too low? She was on Estrace 2mg twice a day. She takes crinone and PIO injections. Her progesterone levels are 30 or higher. Please let me know any advice. We have 3 frozen embryos left and would like to try again, but afraid to waste the embryos. Thank you for your time!

  5. Hi Dr. Sher,
    My Wife had a spontaneous miscarriage at week 4.5 after succesful IUI and her hCG a week later has returned almost to zero (From a peak of 86). We are considering whether its prudent to try again immediately at her next day 1 or wait one cycle to try another IUI or to try again after that – thoughts? Many thanks

    • I would rest 1 cycle.

      Geoff Sher