Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Hello Dr Sher,
I am 39 with diminished ovarian reserve with amh of 0.42, fsh around 12-18. My first IVF cycle was in January, Urofollitropin 225 IU daily was used, triggered 36 hours before the retrieval, follicles were 19-20mm a day before the trigger and we got 4 eggs, 3 mature, 2 fertilized and both turned out to be great quality. Both were transfered and I got pregnant but unfortunately it was ectopic. Treated with a single shot of MTX, was told we can try again in three months. I had my second cycle in June, this time they used Menotrophin 225 IU with the addition of human growth hormone. Did not respond well, only two follicles grew to be 19-20mm,triggered 36 hours before the retrieval, 3 eggs retrieved, all immature. This month they changed protocol, turned into low dose IVF with Clomid and 150 IU Menotrophin every other day and human growth hormone. 3 follicles grew to be 19-20mm, triggered 38 hours before the retrieval. Two eggs retrieved, again all immature. I was told to wait for a few months to try again.
What could be the reason to this? I had mostly mature eggs back in January. Mtx shot could do this or I benefit better from a fsh only stimulant instead of fsh + lh type. My doctor said there should be no difference in response or egg quality. I am really looking for an answer why suddenly my ivf cycles are failing with all eggs being immature.
Also do you suggest correcting a T shaped uterus through surgery prior to transfer?
I should add that despite dor and high fsh, my lh tested around 5-6 on cd3 two cycles in a row.
Hi,Dr.Sher!
I am 43,AMH 0,67 ,FSH 9,7. During my last IVF I had Letrozol from day 3 to day 7 and after that Gonal F and Cetrotide.The follicles were 6 but they didn’t want to grow fast.However,in the end there were three eggs,two embryos,but only one survived.I had a transfer on day two,but the result was negative.Next time the doctor wants to use only Gonal.My question is whether it is a good decision and will Gonal be enough(without letrozol)?
Hlo sir,my get treatment of ivf on 26th june and urine and blood was held on 16july but there is negative result in urine test but in blood test there is 6.6 is there any of pregnancy or not sir plz tell me
Unfortunately this does not look promising.
Geoff Sher
My wife and I are on day 7 of the ivf medication cycle and today we were suppose to start the Ganirelix injection shot but, I gave her the ovidrel by accident. Is there anything that we can do to stop that process from happening?
I doubt it. This, in my opinion could completely foil this cycle. Discuss with your personal RE.
Geoff Sher
Hi Dr.,
With regards to PGS testing, some consultants say that with older eggs the abnormal cells are pushed to the trophoblast (the part that is biopsied) to protect the core and the inner mass is ok..then they auto correct with development. So, I’m wondering if you could get potential false readings from PGS and discard perfectly good embryos. Is there an argument to do regular IVF, based on this and that embryos might self correct? Thank you.
That is unsubstantiated information…I don’t buy it at all!
Geoff Sher