Ask Our Doctors – Archive

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

19,771 Comments

  1. Hi Dr Sher,

    We recently had a 9 cell day 3 embryo transferred and for the first time ever we got a positive pregnancy test. I am 36. Sadly we had our first scan at 6.5 weeks and they couldn’t find a gestational sac that would be anywhere near the right size for that stage of pregnancy. My hcg was measured and was only 119 although pregnancy tests were still coming back strongly positive. We have 4 frozen day 5/6 blastocysts all at either hatching or expanded stage. Are we likely to have more luck with these? I’m really worried that because this embryo wasn’t viable we are now doomed to fail. It’s hard to think positive again.

    • Not at all! This might simply have been bad luck!

      So sorry!

      Geoff Sher

  2. Hi Dr Sher.. After 5 years of trying, one ectopic pregnancy (before we started trying), and 7 IVF cycles, We are finally pregnant naturally.. However I am really nervous, since this is the first time I have actually known I am pregnant..
    my HCG levels at 4w5d were 267.17 mIU/ml.
    because the doctor knows my history, I would assume that she would order more betas to check doubling time. However she did an ultrasound and she saw a gestational sac and all seemed to be in order. However, she did give me a shot of HCG (10,000) to support the pregnancy. At the time I was too shocked to react, but I read up about it and it seems to be an acceptable practice. My question is.. I suspect my HCG level maybe low.. even in case it isnt, how do I now check the doubling? I will have synthetic HCG in my system as well..
    I know it is said that with the shot about a 1000 mg are lost per day.. so will I just need to adjust accordingly?
    Also is 267.17 a good HCG number for 4w5d?

    • The only way tofollow now is withserial US examinations.

      Good luck!

      Geoff Sher

  3. Dear Dr. Sher,
    If LH falls below 1 in a CD10, would it compromise the eggs?

    • f you are on 75U of menotropin (e.g Menopur), which contains FSH and hCG with a small amount of LH), the hCG which acts like LH would supplant the need for additional LH.

      Geoff Sher

  4. Hi Dr. Sher,
    Recently we found out my husband has 100% sperm antibodies in his system. We are going for a second opinion in a weeks time but I just wanted to know do u think there is a chance for us to naturally conceive? I do not have any fertility issues. I am 26yrs old and my husband is 29.

    • No! You need IVF with ICSI.

      Geoff sher

  5. Hi Dr Sher,
    I have Hashimoto’s. Does that mean I must also have a high amount of NKC (Natural Killer Cells)? My TSH, T3 and T4 have always been closely monitored by an endocrinologist. My husband and I have been unable to conceive for over a year. I had one chemical pregnancy in October 2014.
    Thank you for your time.

    • The fact that almost 50% of women who harbor antithyroid antibodies do not have activated CTL/NK cells suggests that it is NOT the antithyroid antibodies themselves that cause reproductive dysfunction. The activation of CTL and NK cells that occurs in half of the cases with TAI is probably an epiphenomenon with the associated reproductive dysfunction being due to CTL/NK cell activation that damages the early “root system” (trophoblast) of the implanting embryo. We have shown that treatment of those women who have thyroid antibodies + NKa/CTL using IL/steroids, improves subsequent reproductive performance while women with thyroid antibodies who do not harbor NKa/CTL do not require or benefit from such treatment.

      Please visit my new Blog on this very site, http://www.DrGeoffreySherIVF.com, find the “search bar” and type in the titles of any/all of the articles listed below, one by one. “Click” and you will immediately be taken to those you select. Please also take the time to post any questions or comments with the full expectation that I will (as always) respond promptly
      •Immunologic Implantation Dysfunction (IID) & Infertility (IID):PART 1-Background
      •Immunologic Implantation Dysfunction (IID) & Infertility (IID):PART 2- Making a Diagnosis
      •Immunologic Dysfunction (IID) & Infertility (IID):PART 3-Treatment
      •Thyroid autoantibodies and Immunologic Implantation Dysfunction (IID)
      •Immunologic Implantation Dysfunction: Importance of Meticulous Evaluation and Strategic Management:(Case Report
      •Intralipid and IVIG therapy: Understanding the Basis for its use in the Treatment of Immunologic Implantation Dysfunction (IID)
      •Natural Killer Cell Activation (NKa) and Immunologic Implantation Dysfunction in IVF: The Controversy!
      •Traveling for IVF from Out of State/Country–
      •A personalized, stepwise approach to IVF

      Please call or email Julie Dahan, my patient concierge. She will guide you on how to set up an in-person or Skype consultation with me. You can reach Julie at on her cell phone or via email at any time:
      Julie Dahan
      •Email: Julied@sherivf.com
      •Phone: 702-533-2691

      I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.