Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Hi, I’m 45-years old and still have a regular cycle. I’ve done IUI since last spring and have not had success. The RE I’m working with isn’t monitoring my cycles closely and we’ve missed a couple of months due to an undiagnosed tube blockage and this last cycle because I ovulated 2 days earlier than I had previously been ovulating. I decided to take the summer off hoping to relax and reorient myself, but, am now about to go back to the RE. Is there any particular protocols I should be asking for? The RE is recommending I stick with IUI and pills no injectables because with my age factor it won’t make a difference in outcome. I’m willing to do IVF but would really like to use my own eggs, if possible.
Hello Dr. Sher I hope you are well I have a question
Is 17 day of Estrofem enough time in a medicated fet to then transfer a 5 day embryo as long as lining ect look ok or is it best to wait a few more day like day 19 thanks
Not enough information for me to give an authoritative opinion…sorry!
Geoff Sher
Hi Dr. Sher,
I had a D and C (vacuum aspiration only) a year ago due to miscarriage. My husband and I are now trying again. Two cycles ago, my lining on the max dose of estradiol was 6.2 mm, and the cycle was canceled. This last month, my lining was 5.5 mm, I started progesterone in oil shots and it got to 6 mm (with a small amount of fluid) two days before transfer. We went ahead, and I became pregnant but miscarried at 4 weeks 2 days. I had an ultrasound today (would be 5 weeks pregnant) and my lining measured 8 mm. Because of this thickness, my Dr does not think the miscarriage was due to thin lining. But our embryo was PGS tested…
Is it possible my lining could have thickened to 8 mm before the transfer but after starting the progesterone shots? If it is 8 mm now, does that mean it is capable of thickening appropriately? My fear is damage from the D and C.
Thank you so much!!
Susan
Hi Susan,
It is the thickness of the lining as measured prior to progesterone exposure that matters. Thickness increases after progesterone because of secretions that build up in the endometrial glands and not due to any increase in endometrial cells. Thus, regrettably, if your lining was <8mm prior to progesterone administration, there is a strong likelihood that this pregnancy might not endure.
I sincerely hope that this prediction turns out to be wrong.
Geoff Sher
Hi Dr. Sher
This might be a silly question but one that has been bothering me.
I had a day 5 blast transfer fresh 3 days ago , today I was have strong period like cramping which I assume/Hope was implantation cramping. However my 34 lb son got hurt at the playground and I picked him up to comfort him, from that time on all cramping ceased. I am wondering if it is possible that if something was implanting my action could have stopped its progress, and I ruined my chance?
I doubt strongly the lifting of your 34lb son would have caused any harm.
Good luck and G-d bless!
Geoff Sher
Hello Dr.,
I am 28 years old and after many test I have been diagnosed with POF. After many failed attempts, my husband and I moved towards egg donor. The donor is a proven donor, who, at time of donation was 24 years old. From her donation we had 29 eggs, of which fertilized to 15 embryos.
-At this point we have done 1 fresh transfer (1, 5 day AA blast) and 1 FET (1, 5 day AA blast).
-I had a Hysteroscopy a year prior and everything was perfect.
-My uterine lining responded perfectly and was at a 10 during time of both transfers. Also was trilaminar
-My doctor did a wave test and it was “0” during time of each transfer as well.
-Due to age we did not PGS test the embryos.
-I have not had any autoimmune testing or ERA test.
-My protocol for transfers have included the following:
*BCP month prior,
*1 mg estradiol (first transfer was vaginally, second transfer was orally) daily,
*.25ML intramuscular Delestrogen every other day
*Then 5 days before transfer I began progesterone.
*I did 400 MG progesterone vaginally 2x a day.
*I also did 1 cc intramuscular daily, for a few days, then increased to 2x a day after wave test and continued with 2x a day until after day of transfer.
*I went back to 1 cc daily and 2 vaginal capsules daily day after transfer.
*2 days before transfer and including day of transfer I took Doxycycline 2x a day.
*I also started medrol dose pack 2 days before transfer and continue with protocol for the whole 6 day pack.
*My first fresh transfer I was on lovenox as my PTT was slightly elevated, for the FET I only took baby aspirin.
*I also take Vitamin D, Vitamin C, CoQ 10, Prenatals, Selenium, and L Arginine.
Both cycles resulted in BFN. I am feeling so hopeless. I love my Doctor and Facility as they have started to feel like family, but I cannot imagine trying another time without looking into other tests or possibilities for why my previous 2 transfers failed. Any advice on questions to ask or tests to run? I always imagined donor eggs with such a young donor would be easier. My husband showed slightly low sperm count but everything else was normal and he still had MORE than plenty to fertilize eggs, doctor was not concerned with this.
I have read it can take more than a few tries, but I am feeling hopeless!
Thank you