Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Would you consider transferring any of these or are they no worth it?
Embryo 00326-1M is missing two pieces of chromosome 1 in 40% of cells, has three copies of chromosome 14 (trisomy 14), extra pieces of chromosome 16, and three copies of chromosome 22 (trisomy 22)
Embryo 00327-2M is missing one copy of chromosome 19 (monosomy 19)
Embryo 00327-3M has extra pieces of chromosome 3 in 70% of cells, missing one copy of chromosome 14 (monosomy 14) in 40% of cells, and has three copies of chromosome 20 (trisomy 20)
I am 42. Was pregnant twice at 41…first baby made it almost 4 months but had cystic hygroma but no identifiable genetic issue….second was early miscarriage–I have 2 other children that were healthy.
This is very concerning! In my opinion only one embryo (Embryo 00327-2M) is worth trying by way of transfer. The remainder are all complex aneuploid and in my opinion should be discarded. Discuss with your RE.
Geoff Sher
Hi Dr. Sher,
I have an aneuploid embryo ( Trisomy 15) should transfer be attempted or should I discard this embryo?
Hi Geoff,
I had an early MMC with my first FET using a PGD normal 5 day blast, identified around scan at 6 weeks 6 days (gest sac, yolk sac + small fetal pole seen, no heartbeat. Re scanned 5 days later and there was no change at all). 6 months later have had another FET with another PGD rested 5day blast and these are my HCG levels. I had a small bleed yesterday so had a scan today (would be 5weeks 5days) and gest sac + yolk sac seen. I am being re scanned in 10 days and continuing with progesterone support via PIO and suppositories.
13 dpt- 950, prog 24
18 dpt- 3600, prog 51
20 dpt- 5700, prog 24
Any thoughts on those levels would be so much appreciated, the rise from 18dpt to 20dpt doesn’t seem ideal. I have been reading a lot of your responses and has been very insightful, thank you.
Many thanks
I have seen viable pregnancies under similar circumstances. However, you should do an US in 1 week, that should give a definitive answer.
Good luck!
Geoff Sher
Hi Dr Sher
My frozen embroyo transfer was on 3rd April, 5day , grade A and genetically tested embroyo. I am 34.
First HcG test was conducted on 13 april 24.6
And second HcG was on 15 april and came 86.
What are my chances of having a pregnancy ?
Looks promising!
Good luck and stay safe!
Geoff Sher
Is it normal for the heart rate to be only 147bpm at 9w3d, the same as it was 2 weeks earlier? Also when is it safe to come off progesterone? How high should my levels be without medication?
Completely normal!
Be safe!
Geoff Sher
Hello Doctor, how are you?
i am suffering with dark brown discharge in mid cycle. My period was on 29th march. And from yesterday that is from 15th april happening this. This is first time i am observing. One more thing i was taking the ivf treatment i did almost 1&half month cource of medicines. My blastocyte transfer was on 26th april but my transfer stopped due to corona lockdown but i took 5 progesterone injection till 26th. Please suggest is this normal discharge? Or something is wrong thing happening.i am very scared.also we didnt have intercource from last period so implantation bleeding is not possible.
Vaginal bleeding occurs in about 25% of all pregnancies. When it happens, it almost invariably raises the concern of pregnancy loss (miscarriage). Bleeding can also be a sign of a tubal (ectopic) pregnancy, and in cases where the distended Fallopian tube ruptures it can precipitate a life-threatening crises. However, a small amount of painless vaginal bleeding can also be the result of normal embryo implantation (i.e. implantation bleeding) or it can result a local erosion of the vagina or cervix and/or trauma during intercourse.
Notwithstanding, in virtually all cases the occurrence of early pregnancy vaginal bleeding congers concerns or even alarm regarding the possibility of miscarriage. And when this happens to women who conceived following infertility treatment, the alarm often turns into panic. However, the truth is that in most such cases the bleeding soon stops and the pregnancy proceeds unabated to the birth of a healthy baby. However, because some do progress and end in miscarriage, and in most cases, only time will tell how things will ultimately turn out, we use the term “threatened miscarriage” to describe such early bleeding. The term “inevitable miscarriage” is used once symptoms and signs confirm a miscarriage is in progress. The term “complete miscarriage” is used if all products of conception are passed, leaving the uterus “empty”. An “incomplete miscarriage” refers to cases where some products remain retained in the uterus.
Miscarriage: Mild painless vaginal bleeding (often referred to as “spotting”) is usually due to hormonally induced eversion of the glandular cells that line the inner cervical canal, such that erosion develops on the outer part of the cervix that protrudes onto the vagina. The everted glandular tissue is fragile and susceptible to contact trauma, brought about sexual penetration or the insertion of vaginal suppositories. Since such local bleeding does not involve the developing conceptus located inside the uterus it is almost always innocuous. The diagnosis of a local cause of bleeding requires visual inspection of the vagina and cervical inlet a speculum examination. Thereupon, provided that the pregnancy has advanced beyond 5-6 weeks, a concomitant sonogram could confirm the presence of an unaffected pregnancy. Patients are advised to be more careful in inserting vaginal suppositories and to avoid sexual penetration until the bleeding has stopped for at least 1 week.
Be safe!
Geoff Sher
Hello
I am 28years old. I had 2 miscarriages in 2018 (1st MMC @9 weeks, baby stopped growing at 6.5. 2nd a chemical @ 5weeks). The following month i conceived again and resulted in a beautiful son. I am now ttc again and have since had 2 miscarriages totalling 4, both @ 6weeks and even with the addition of clexane, cylogest and low dose aspirin). My dr has now prescribed predisnolone. Can you advise whether you think it may be high NK cells or should I go private for karyotyping tests?