Ask Our Doctors – Archive

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

19,771 Comments

  1. I have had a blood test for NK cells which came back elevated at 15%. A biopsy for uterine NK cells came back clear (though this was done during the first half of my cycle) I am thinking of having an endometrial scratch ahead of my upcoming FET, would you recommend this?

    • Respectfully April, I would believe the NKa blood test (provided it was the K-562 target cell test) over the endometrial biopsy…for sure. Also, I do not believe the “endomemetrial scratch” has any proven merit.

      I strongly recommend that you visit http://www.DrGeoffreySherIVF.com. Then go to my Blog and access the “search bar”. Type in the titles of any/all of the articles listed below, one by one. “Click” and you will immediately be taken to those you select. Please also take the time to post any questions or comments with the full expectation that I will (as always) respond promptly.

      •Controlled Ovarian Stimulation (COS) for IVF: Selecting the ideal protocol
      •IVF: Factors Affecting Egg/Embryo “competency” during Controlled Ovarian Stimulation(COS)
      •The Fundamental Requirements For Achieving Optimal IVF Success
      •Ovarian Stimulation for IVF using GnRH Antagonists: Comparing the Agonist/Antagonist Conversion Protocol.(A/ACP) With the“Conventional” Antagonist Aproach
      •Anti Mullerian Hormone (AMH) Measurement to Assess Ovarian Reserve and Design the Optimal Protocol for Controlled Ovarian Stimulation (COS) in IVF.

      •The Role of Immunologic Implantation Dysfunction (IID) & Infertility (IID):PART 1-Background
      •Immunologic Implantation Dysfunction (IID) & Infertility (IID):PART 2- Making a Diagnosis
      •Immunologic Dysfunction (IID) & Infertility (IID):PART 3-Treatment
      •Thyroid autoantibodies and Immunologic Implantation Dysfunction (IID)
      •Immunologic Implantation Dysfunction: Importance of Meticulous Evaluation and Strategic Management:(Case Report
      •Intralipid and IVIG therapy: Understanding the Basis for its use in the Treatment of Immunologic Implantation Dysfunction (IID)
      •Natural Killer Cell Activation (NKa) and Immunologic Implantation Dysfunction in IVF: The Controversy!
      •Endometrial Thickness, Uterine Pathology and Immunologic Factors
      •Vaginally Administered Viagra is Often a Highly Effective Treatment to Help Thicken a Thin Uterine Lining
      •Traveling for IVF from Out of State/Country–
      •A personalized, stepwise approach to IVF
      •How Many Embryos should be transferred: A Critical Decision in IVF.
      Please call or email Julie Dahan, my patient concierge. She will guide you on how to set up an in-person or Skype consultation with me. You can reach Julie at on her cell phone or via email at any time:
      Julie Dahan
      •Email: Julied@sherivf.com
      •Phone: 702-533-2691
      ?800-780-7437

      Geoff Sher

      I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.

  2. I’m 38, have 3 kids (youngest is 7) and have pcos, endometriosis, and haven’t had a period for 6 years now. I had an IUD in after the last child but had it removed 3 years ago. Still, no period. I am 100 lbs overweight. I cannot lose weight without RX drugs to basically starve myself. Suggestions?

    • Hi Valorie,
      There is unfortunately no easy answer. Sometimes Metformin will help. Discuss with your endocrinologist and talk to a nutritionist.

      Geoff Sher

  3. Hello dr sher, My name is Jillesia I’m 26y/o. I suffer from pcos. I’m over weight. I’ve tried clomid once years and my ovaries did not respond. I also tried fermara last month with no success. My dr told me that iui or ivf is looking like my next step. I wanted to know if you had any advice for me. I also want to know approximately how much do you charge for iui amd ivf and what are the payment options?

    • Please call Julie at 800-780-7437 and she will help you access the information.

      Geoff Sher

  4. What is the success rate of a woman with PCOS achieving ovulation after the age of 35? Even more so, what if the woman has been an-ovulatory since puberty?

    • It is probably possible to induce ovulation in the vast majority, but it would require an individualized approach. For example, clomiphene or letrozole would not likely work in cases where menstruation ceases or as spaced months apart. In such cases, injectible gonadotropins will usually be successful in inducing ovulation.

      Geoff Sher

      Geoff Sher

  5. Dear Dr Sher,
    4 questions:
    1)What happens if a trigger shot is given a few hours after a natural surge? Does it split the already split egg again or does it have no effect or does it make the egg useless?
    2) In a totally natural cycle, is egg retrieval done after a natural surge without trigger?
    3) If one can determine exact timeframe of surge (for example no surge at 2pm and surge at 4pm) can egg retrieval be done to collect the egg successfully if retrieval is done within 36 hours?

    4)In such a case is it beneficial to do egg retrieval after the natural surge or better to give trigger shot in addition before retrieval?

    • 1)What happens if a trigger shot is given a few hours after a natural surge? Does it split the already split egg again or does it have no effect or does it make the egg useless?

      A: It wont split the egg and probably will have no effect

      2) In a totally natural cycle, is egg retrieval done after a natural surge without trigger?

      A: Can be

      3) If one can determine exact timeframe of surge (for example no surge at 2pm and surge at 4pm) can egg retrieval be done to collect the egg successfully if retrieval is done within 36 hours?

      A: doing it 36 h after detection may be too late

      4)In such a case is it beneficial to do egg retrieval after the natural surge or better to give trigger shot in addition before retrieval

      A: After a trigger hCG shot that is given just prior to the surge or with no trigger about 28-30h after a natural surge is detected.

      Geoff Sher