Ask Our Doctors – Archive

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

19,771 Comments

  1. Hi Dr. Sher,
    I am going to use viagra suppositories with this FET attempt to try and stop my lining from shrinking. It shrinks significantly once progesterone starts and noone knows why. I have a host of things wrong with me (NK, MTHWR, high T cells).

    Online, you said the suppositories are 20mg/ 4 times a day, but in your article it say 25mg 4 times/day. The pharmacy says they only make 25mg. I think you may have a typo??

    Also, I just did baselines today, day 2 for my FET cycle. My doctor says I should start the Viagra today with the estrogen pills, but I read in your research to start it after bleeding ceases until progesterone starts. Is that correct?

    Thanks!

    • Oops! My slip-up.T IS 25mg.

      It wont matter whether you start after bleeding or during bleeding. he only problem with using it when you are bleeding as that this can affect absorption somewhat.

      Geoff Sher

    • Hi Dr. Sher,
      I wrote you about taking viagra for a FET to hopefully help my lining from shrinking once I started progesterone. I thought it may make my lining thicker so the shrinkage would be less. I took it from day 3 until day 12 (yesterday) when I started my progesterone and did a hcg trigger. My doctor told me to stop it last night. My transfer is in 5 days.

      My lining was a 9 yesterday and an 8 today. I am worried it will continue to shrink as it has done in the past. In the past it would be a 9 when progesterone started and then a 5 several days later, the day before transfer, resulting in cancellation.

      Is there any research looking at the effects of continuing Viagra for a few more days?
      And do you know any research on why linings shrink a lot after progesterone begins? Is that normal? Is it bad if it shrinks a lot? Or does that not matter?

      What do you recommend?

      Thanks,
      Brittany

  2. Hello! My 5 days transfer Eason oct 1. My beta at 11dpt5dt was: 116. I’m concern it’s low compared with other women. Help!

    • Hi Varie,

      Much more important is whether the beta doubles over 2 days. Ultimately it will be the US that will say it all …roughly 2.5 weeks after the 2nd beta.

      Geoff Sher

  3. I have an arcuate uterus (1-2cm thicker than normal) and am currently 22 weeks pregnant. I turned down the corrective surgery because I was not convinced the procedure would make things better. Now I am worried that it could endanger my precious boy. There seems to be very little research when it comes to success rates with my diagnosis. I was wondering what your thoughts were?

    • Your doctor needs to monitor your uterine activity and start uterine tocolytics (relaxants) if activity increases abnormally. By the way, I do not think you made the wrong decision to avoid the surgery.In my opinion it could have done more harm than good..

      Geoff Sher

  4. Dr. Sher,

    Thank you so much for your detailed response below to our question about estrogen priming (see old post below). One LAST question, if you don’t mind.

    With estrogen priming, do you recommend taking 125 mcg of Ganirelix WHILE taking the E2V injections?

    THANK YOU in advance!

    Old posts below:
    Hello Dr. Sher,
    To clarify on my previous post that you responded to earlier today.
    I’m 37 years old and have severe DOR. My AMH is 0.23 and my basal Day 3 FSH has been as high as 18, LH is typically 5.3 and E2 51. I have failed 3 IVF cycles, two of which have had several or all “empty follicles” which I know there is no such thing as an empty follicle as the stimulation can impact the ‘stickiness’ within the follicle or perhaps my eggs are grossly chromosomally abnormal. Two of cycles were Antagonist (one with HGH and one without) and one Microdose Lupron Flare. I am looking at the A/ACP (Agonist/Antagonist Conversion Protocol) before moving to donor eggs.
    Q: Do you recommend estrogen priming?
    A: You could…it is a toss-up. I usually reserve estrogen priming for when I start the cycle with a maximum dosage of FSH of 750 U per day….and usually restrict this to women with an AMH of <0.1ng/ml. With priming, I do not use Estrace. I prescribe Estradiol Valerate (E2V) intramuscularly administered twice weekly.

    • I think, in your case, if you decide to go with estrogen priming, I would suggest 250mcg daily. Also bear in mind that with this protocol, progress can be slower after the stimulation is initiated and it often takes 3-5 days longer than otherwise, for follicles to reach their optimum size.

      Geoff Sher

  5. Sorry typo I had 4 frozen embryo with grace A quality . Iam 32 years old , no uterine abnormalities , male factor infertility – low motility . I conceived naturally three years before but had a miscarriage at 17 weeks due to incompetent cervix . My FET biopsy showed normal embryo .