19,771 Comments

1. Kim on October 24, 2016 at 10:02 pm

   Dr.Sher,
   What are your thoughts on the use of N-Acetyl cysteine? I took it thru egg retrievals and up to my FET. I only had one chromosomally normal embryo and transferred it. I saw a study from 2008 that says the supplement reduces miscarriages. I want to continue using it but my RE doesn’t really believe in any supplements or “non-western” medicine. Do you advise your patients against its use after transfer?

   • Dr. Geoffrey Sher on October 24, 2016 at 11:26 pm

     Sorry kim,

     i have no knowledge to support the use of this supplement having any meaningful benefit.

     Sorry!

     Geoff Sher

2. Cassie on October 24, 2016 at 8:50 pm

   Hello Dr. Sher,

   Is it true that DQ Alpha, HLA testing and ATA is really only needed if there are NKA cells? I believe I read in one blog of yours that IF you show activated NKA cells, then you have to do further testing… Is that correct? Thank you very much.

   • Dr. Geoffrey Sher on October 24, 2016 at 9:40 pm

     Yes indeed! That is so!

     Geoff Sher

3. Melissa on October 24, 2016 at 6:48 pm

   Hi Dr. Sher,

   I’m 43, and have just completed my 2ND IVF process. At 11dp3dt, my beta was 76, and the nurse called to tell me I was “very pregnant.” My beta was repeated today at 15dp3dt, but my beta has only increased to 187. At the time of transfer, 4 embryos were implanted. At this point, is all hope lost? My beta test will be repeated in 2 days.

   Thank you very much.

   Melissa

   • Dr. Geoffrey Sher on October 24, 2016 at 9:52 pm

     Keep repeating the beta test every 2 days to see if it picks up. It really needs to double about every 48 hours in early pregnancy.

     Geoff sher

4. Mandy on October 24, 2016 at 5:17 pm

   Hi Dr Sher
   Could you please give me your view on ERA test?
   I have had two failed cycles using own embryos and one failed using donated embryos

   • Dr. Geoffrey Sher on October 24, 2016 at 5:38 pm

     Respectfully mandy, I do not have any confidence in it value and do not use it with my patients.

     Good luck!

     Geoff Sher

5. S.O. on October 24, 2016 at 4:48 pm

   What is the underlying cause of increased circulating LH in women with DOR? Can insulin resistenance (without PCOS or DOR) cause the same?

   • Dr. Geoffrey Sher on October 24, 2016 at 5:37 pm

     In women with DOR, declining eggs in the ovaries elicit a feedback response by the hypothalamus in the brain that causes the pituitary gland to increase output of basal FSH and LH.

     In women with PCOS, elevated LH is a genetic component of the condition.

     Geoff Sher