Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Dr. Sher,
Unfortunately my recent pregnancy ended in miscarriage at around 6 weeks. I had a d&c so that we could send the embryo/fetus for testing however there was bacterial contamination and the lab could not do the chromosome testing. We have three frozen embryos left, none PGS tested, we had a total of 6 from this cycle-one fresh transfer that did not result in pregnancy and two transferred with FET which resulted in a singleton pregnancy and ended up in miscarriage. My concern is gearing up for another FET with all the medication and transferring a non PGS tested embryo. Is it dangerous to thaw the remaining 3 embryos, biopsy them and then refreeze them? We just can’t see transferring another embryo if it potentially could be abnormal and lead to miscarriage.
Some say that the thaw to PGS-test is not harmful. I am of a different opinion. I consider it to be ill-advised to thaw blastocysts, biopsy them and then refreeze them only to have to re-thaw them again for FET. However, if the embryos were frozen early (pronucleates or day 3-5, then I would not have a problem in these being thawed, taken to blastoicyst for biopsy and then refrozen …as the latter gives the embryos an opportunity to recover while development to blastocysts.
Geoff Sher
Hello Dr Geoffrey… I had my embryo transfer on 19th Nov… 3 embryos were transferred frozen…my beta hcg on 29th Nov was 61… which went to 664 on 3rd Dec and on 10th it has been 1888.81… on 10th Dec eve had a severe abdominal cramps along with brown discharge… which progressed to fresh mild bleed in mornin… the pain subsided on takin a dicycloamine tablet.. the bleeding is thr on nd off… imdoes it look like a impending miscarriage??
It could be that the pregnancy is failing. Have an US done to see if a gestational sac is visible.
Good luck!
Geoff Sher
Dear Dr Sher, I think that I have been oversuppressed on Lupron . I started taking 20 units a day on November 2nd . My e2 530 rose and I had two foliciles . My dr told me to keep taking the Lupron . His plan was to wait until My e2 was under 50 and LH under 5. That happened on 11/28 he droped the Lupron to 2 units and started me on Gonal F 150. After two days I started to bleed . My estrogen continued to fall to below 5. I have been at below 5 for 12days .He increased Gonal F from 150,to 225 then 350 and finaly 600 iu .Twelve days in total I have an estrongen of below 5. He told me to stop all meds and That I am going through menopause. Will my overies recover ? Should I see someone else immediately or should I wait for awhile. I feel very sick and sad that I spent $5000 to make my situation worse. Can you advise
Hi Marguerite,
There is not enough information for me to comment authoritatively. Please call and set up a Skype consultation with me to discuss.
I strongly recommend that you visit http://www.DrGeoffreySherIVF.com. Then go to my Blog and access the “search bar”. Type in the titles of any/all of the articles listed below, one by one. “Click” and you will immediately be taken to those you select. Please also take the time to post any questions or comments with the full expectation that I will (as always) respond promptly.
•The IVF Journey: The importance of “Planning the Trip” Before Taking the Ride”
•Controlled Ovarian Stimulation (COS) for IVF: Selecting the ideal protocol
•IVF: Factors Affecting Egg/Embryo “competency” during Controlled Ovarian Stimulation(COS)
•The Fundamental Requirements For Achieving Optimal IVF Success
•Ovarian Stimulation for IVF using GnRH Antagonists: Comparing the Agonist/Antagonist Conversion Protocol.(A/ACP) With the “Conventional” Antagonist Approach
•Ovarian Stimulation in Women Who have Diminished Ovarian Reserve (DOR): Introducing the Agonist/Antagonist Conversion protocol
•Anti Mullerian Hormone (AMH) Measurement to Assess Ovarian Reserve and Design the Optimal Protocol for Controlled Ovarian Stimulation (COS) in IVF.
•The “Biological Clock” and how it should Influence the Selection and Design of Ovarian Stimulation Protocols for IVF.
• A Rational Basis for selecting Controlled Ovarian Stimulation (COS) protocols in women with Diminished Ovarian Reserve (DOR)
•Diagnosing and Treating Infertility due to Diminished Ovarian Reserve (DOR)
•Controlled Ovarian Stimulation (COS) in Older women and Women who have Diminished Ovarian Reserve (DOR): A Rational Basis for Selecting a Stimulation Protocol
•Optimizing Response to Ovarian Stimulation in Women with Compromised Ovarian Response to Ovarian Stimulation: A Personal Approach.
•Human Growth Hormone Administration in IVF: Does it Enhances Egg/Embryo Quality and Outcome?
•The BCP: Does Launching a Cycle of Controlled Ovarian Stimulation (COS). Coming off the BCP Compromise Response?
Please call or email Julie Dahan, my patient concierge. She will guide you on how to set up an in-person or Skype consultation with me. You can reach Julie at on her cell phone or via email at any time:
Julie Dahan
•Email: Julied@sherivf.com
•Phone: 702-533-2691
?800-780-7437
Geoff Sher
I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.
I just did a FET of a 5 day blastocyst on 11/28. First beta showed 277 HCG and the 48 hour follow up had jumped to 938. Is that a possible indicator of twins? We only had one blastocyst transferred and so I was surprised by the huge jump.
Probably one but yes…it could be uniovular twins!
Good luck!
Geoff Sher
Firstly want to thank for creating this forum,it is indeed helpful.I would like to know if you have a branch in dallas Texas,
Yes we do. Contact Sher Institute in Dallas and ask for an appointment with Dr Saleh! Give him my regards.
Geoff Sher