Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Dear Dr Sher , for Immunologic implantation dysfunction , what is the Intralipids and the steroids protocol please? Thank you for sharing
100cc, 20% IL diluted in 500ccof normal saline and infused 10-14 days prior to ET…over 3-4 hours. Repeated with the +ve beta hCG test and in cases of alloimmune implantation dysfunction (partial DQ alpha match) every 2-4 weeks thereafter until the 24th week of pregnancy. Dexamethasone 0.75mg orally daily from the beginingof ovarian stimulation until the 8th week of pregnancy and tailed off in the ensuing 2 weeks…or earlier if pregnancy does not occur or fails.
Good luck!
Geoff Sher
Hi I am wondering if I have a ultrasound on Monday 3/21 I will be 25dpo or 20dp5dt what can we expect to see on it or for them to find on it we transferred 2 fresh embryos on 3/1 a day 5 transfer.
I already have adressed this earlier today!
Geoff Sher
Hi Dr. Sher,
I’m 43 and turning 44 end of November. I’m taking CO-Q10, DHEA, and some parts of the month black cohosh (first 10 days). I have a high BMI which I will bring DOWN to 43 by the summer. I have trouble with my weight, but I’ve just lost about 10 lbs and so I see hitting my summer goal.
I’ve completed 4 failed IUIs, and have two more prior moving to IVF. Two of those completed were clomid 100 cycles with Crinone (progesterone).
I am hopeful for IVF considering the steps I’m taking. I would love to use my my own eggs, but I’ve asked my sister if she would donate as a backup plan (she’s 38), if she agrees, it would be great. She has not yet agreed and is thinking about the moral/personal reasons.
My questions are:
1. given my stats, how much does weight loss impact the developing eggs? How soon will weight loss take effect (do I need to finish getting to the lower BMI before effects take place?)
And 2. other than weight loss and Co-Q10 + supplements, what else should I be doing to improve egg quality/environment? I like yoga, swimming, cycling.
And 3. Insurance will only cover IVF till age 44. Any recommendation on # cycles of IVF with my own eggs should I use before going to donor egg?
My questions are:
1. given my stats, how much does weight loss impact the developing eggs? How soon will weight loss take effect (do I need to finish getting to the lower BMI before effects take place?)
A: It is a good goal to try and get your BMI under 25 but age and its adverse influence on on egg/embryo competency and unfortunately that is inevitable.
And 2. other than weight loss and Co-Q10 + supplements, what else should I be doing to improve egg quality/environment? I like yoga, swimming, cycling.
A: Unfortunately age is the factor. Exercise and life-style changes , although commendable will not likely improve egg quality.
And 3. Insurance will only cover IVF till age 44. Any recommendation on # cycles of IVF with my own eggs should I use before going to donor egg?
If you decide to use your own eggs, my recommendation would be a modified, long pituitary down-regulation protocol. I would use an agonist/antagonist conversion protocol with human growth hormone (HGH) augmentation and would recommend Staggered IVF with embryo banking of PGS (next generation gene sequencing)-normal blastocysts, to make hay while the sun still shines.
Please visit my new Blog at o to http://goo.gl/4hvjoP , find the “search bar” and type in the titles of any/all of the articles listed below, one by one. “Click” and you will immediately be taken to those you select. Please also take the time to post any questions or comments with the full expectation that I will (as always) respond promptly.
•Controlled Ovarian Stimulation (COS) for IVF: Selecting the ideal protocol
•Ovarian Stimulation for IVF using GnRH Antagonists: Comparing the Agonist/Antagonist Conversion Protocol.(A/ACP) With the“Conventional” Antagonist Aproach
•IVF: Factors Affecting Egg/Embryo “competency” during Controlled Ovarian Stimulation(COS)
•Anti Mullerian Hormone (AMH) Measurement to Assess Ovarian Reserve and Design the Optimal Protocol for Controlled Ovarian Stimulation (COS) in IVF.
•The “Biological Clock” and how it should Influence the Selection and Design of Ovarian Stimulation Protocols for IVF.
•Diagnosing and Treating Infertility due to Diminished Ovarian Reserve (DOR)
•Human Growth Hormone Administration in IVF: Does it Enhances Egg/Embryo Quality and Outcome?
•The BCP: Does Launching a Cycle of Controlled Ovarian Stimulation (COS). Coming off the BCP Compromise Response?
•Frozen Embryo Transfer (FET): A Rational Approach to Hormonal Preparation and How new Methodology is Impacting IVF.
•Staggered IVF: An Excellent Option When. Advancing Age and Diminished Ovarian Reserve (DOR) Reduces IVF Success Rate
•Embryo Banking/Stockpiling: Slows the “Biological Clock” and offers a Selective Alternative to IVF-Egg Donation.
•Preimplantation Genetic Sampling (PGS) Using: Next Generation Gene Sequencing (NGS): Method of Choice.
•IVF Failure and Implantation Dysfunction: The Role of Endometrial Thickness, Uterine Pathology and Immunologic Factors
•Why did my IVF Fail
•Traveling for IVF from Out of State/Country–
•A personalized, stepwise approach to IVF
•How Many Embryos Should be Transferred: A Critical Decision in IVF.
•The Role of Nutritional Supplements in Preparing for IVF
I invite you to call 702-699-7437 or 800-780-7437 or go online on this site and set up a one hour Skype consultation with me to discuss your case in detail.
I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.
Geoff Sher
I invite you to call 702-699-7437 or 800-780-7437 or go online on this site and set up a one hour Skype consultation with me to discuss your case in detail.
I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.
Geoff Sher
Good morning Dr. Sher, can muti fibroid cause preterm labor at 20 weeks? 4 is outside the uterus, 1 is in the wall of the uterus and they are all between 5 – 6 cm. Thanks
Yes it can do!
Geoff Sher
Hello! I’m seeking for advice. I’m 31 and my husband is 32. We’re healthy and live a pretty healthy lifestyle. We’ve been trying to have a baby for 2,5 years. We’ve done 2 IUI and 3 IVFs. I’ve never been pregnant. I have only one ovary since the other one was removed as a baby due to ovarian torsion. Also they had to remove a cyst from my other ovary as well. My AMH level is only 0.3 and my eggs seem to be bad quality. Our embryos are slow and stop dividing. On the first IVF we had 8 mature eggs, 5 fertilized, 4 made it to day 3 but they were slow and never made it to morula or blastocyst stage. IVF 2 we didn’t get to egg retrieval. IVF 3 we had 8 mature eggs, 6 fertilized, 5 made it to day 3. This time on day 3 there were two 8-cell embryos, others were slow again. On day five the other 8-cell embryo had slowed down. The other one was on morula stage, so a bit slow too. We transfered the morula embryo, no pregnancy. So our embryos never make it to blastocyst. What should we do? Is there any chance with my own eggs? Any advice? I’m not sure if I want donor eggs or embryos.
It is in my opinion its all about using the ideal protocol for ovarian stimulation. I would suggest a modified, robust, long pituitary down-regulation protocol. I would use an agonist/antagonist conversion protocol with human growth hormone (HGH) augmentation and would recommend Staggered IVF with embryo banking of PGS (next generation gene sequencing)-normal blastocysts, to make hay while the sun still shines.
Please visit my new Blog at o to http://goo.gl/4hvjoP , find the “search bar” and type in the titles of any/all of the articles listed below, one by one. “Click” and you will immediately be taken to those you select. Please also take the time to post any questions or comments with the full expectation that I will (as always) respond promptly.
•Controlled Ovarian Stimulation (COS) for IVF: Selecting the ideal protocol
•Ovarian Stimulation for IVF using GnRH Antagonists: Comparing the Agonist/Antagonist Conversion Protocol.(A/ACP) With the“Conventional” Antagonist Aproach
•IVF: Factors Affecting Egg/Embryo “competency” during Controlled Ovarian Stimulation(COS)
•Anti Mullerian Hormone (AMH) Measurement to Assess Ovarian Reserve and Design the Optimal Protocol for Controlled Ovarian Stimulation (COS) in IVF.
•The “Biological Clock” and how it should Influence the Selection and Design of Ovarian Stimulation Protocols for IVF.
•Diagnosing and Treating Infertility due to Diminished Ovarian Reserve (DOR)
•Human Growth Hormone Administration in IVF: Does it Enhances Egg/Embryo Quality and Outcome?
•The BCP: Does Launching a Cycle of Controlled Ovarian Stimulation (COS). Coming off the BCP Compromise Response?
•Frozen Embryo Transfer (FET): A Rational Approach to Hormonal Preparation and How new Methodology is Impacting IVF.
•Staggered IVF: An Excellent Option When. Advancing Age and Diminished Ovarian Reserve (DOR) Reduces IVF Success Rate
•Embryo Banking/Stockpiling: Slows the “Biological Clock” and offers a Selective Alternative to IVF-Egg Donation.
•Preimplantation Genetic Sampling (PGS) Using: Next Generation Gene Sequencing (NGS): Method of Choice.
•IVF Failure and Implantation Dysfunction: The Role of Endometrial Thickness, Uterine Pathology and Immunologic Factors
•Why did my IVF Fail
•Traveling for IVF from Out of State/Country–
•A personalized, stepwise approach to IVF
•How Many Embryos Should be Transferred: A Critical Decision in IVF.
•The Role of Nutritional Supplements in Preparing for IVF
I invite you to call 702-699-7437 or 800-780-7437 or go online on this site and set up a one hour Skype consultation with me to discuss your case in detail.
I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.
Geoff Sher
I invite you to call 702-699-7437 or 800-780-7437 or go online on this site and set up a one hour Skype consultation with me to discuss your case in detail.
I also suggest that you access the 4th edition of my book ,”In Vitro Fertilization, the ART of Making Babies”. It is available as a down-load through http://www.Amazon.com or from most bookstores and public libraries.
Geoff Sher