Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
I’m 40 years old. My husband has no MFI. Just went through 2 IVF cycles that produced 9 eggs (7 fertilized) and 7 eggs (5 fertilized). First cycle ended with 2 on day 6 to biopsy for PGS. 2nd cycle yielded zero on day 6. Gutted! My dr says egg quality and already told me to think about donor eggs!! It makes me feel like he is giving up without putting forth effort to try other protocols, try something else.
2 years ago I went through 2 cycles and yielded 30 eggs (29 fertilized) and 27 eggs (22 fertilized). In the end I only had 5 biopsied total (so I get quality isn’t important, quality is) and we had 2 PGS normal. We have one daughter (the other embryo didn’t stick).
I read a lot, and wonder about what I can do to positively effect the quality of my eggs / the embryos so that more make it to day 5/6. DHEA? HGH?
My dr isn’t into supplements. He put me on lovenox for factor v (this time around… 2 years ago I guess he didn’t test for it). Otherwise we are just doing the stim meds.
I’m feeling like I just need to feel armed with questions and requests for my dr. I think we will do one more round of IVF, and this last one really needs to count! Thank you!!
Hi Dr Sher, I had a frozen embryo transfer today after a freeze-all cycle in October, when my progesterone levels were too high for a fresh transfer. Two frozen 3-day embryos were thawed yesterday and cultured for one day before the transfer. Today, on Day 4, one was morula and one was a blastocyst already. Is it normal? I’m a bit worried the second one is growing too fast.
It sounds promising!
Good luck!
Geoff Sher
Is ovarian drilling recommended for DOR women? Would this help release some of the male androgens in their ovaries?
No! I would advise against this .
Geoff Sher
Hi Dr Sher, can I ask why you give a high dose on your A/ACP protocol? I ask because there is a school of thought out there that says low dose stims are better for egg quality whereas high dose stims fry eggs. I noticed you start the stims off with a bang using high dose stims and then drop down. What is the reason for this? is it to wake up as many sleeping follicles as possible? is that how quality is maintained?
I use a higher dosage in women with DOR. Such women are never at risk of overstimulation (OHSS) regardless of dosage and there is no down-side to doing so because and after occupation of all FSH follicle receptors, any excess gonadotropin is excreted.
Geoff Sher
1. You mention menopur and just wondering if Luveris (rLH) is just as good if not better?
2. What in your view is a good ovarian reserve to do the long cycle you recommend for good ovarian reserve. Is a good ovarian reserve when ones AMH is > 1? Can an AMH close to 1 be a good reserve or not really for a 40+ woman?
Luveris is as good as Menopur.
A normal AMH is >2ng/ml. 1.5-2ng/ml represents a “gray zone) and under 1.5 ng/ml suggests significant DOR.
Geoff Sher