Ask Our Doctors – Archive

Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.

19,771 Comments

  1. Dear Dr Sher
    You had advised that I consider staggered IVF and embryo banking and do a Preimplantation genetic screening due to my age(46). I am now considering back to back IVF cycle, freezing the embryos from the first cycle before testing so that the embyros from both cycles can be tested at once in order to manage the cost(The pre implantation screening in my country is actually more expensive than the entire IVF cycle.) Would this be advisable or is Preimplantation genetic screening more viable with fresh embryos?
    Thank you

    • Thawing embryos to biopsy them …only to refreeze while waiting for the result and then having to thaw again for FET is in my opinion stressful on the embryos and I personally would prefer to avoid this.

      Geoff Sher

  2. Hello Dr. Sher,

    Thanks for taking the time to answer so many questions from everyone!

    I recently have been diagnosed with DOR. (AMH: 0.6, FSH 10, AFC 8)
    We have tried 2 IUI with no success.
    I have high androgens (T – 45 ng/dL (8-48 range) and DHEAS (390 ug/dL (84-378 range)) also have symptoms of hirsutism.
    Before starting IVF i was looking into DHEA as there seems to be a lot of publications behind DHEA for DOR patients. But since it is an androgen precursor now I am thinking i should not as my levels are already high.
    Could the high androgens be effecting my eggs? Could dexamethasone help in reducing the T and DHEAS levels, should I maybe try that before an IVF?

    Thank you!

  3. Can anxiety or fear cause implantation failure / IVF failure?

  4. Hi Dr Sher,

    I started stimulation on long protocol 4 days ago and there was a discrepancy between the prescription dosage and the stimulation schedule and I made a mistake that I just realised after 3 nights of injecting 300 instead of 225 of gonal f. What should I do? The clinic has said just to continue with 225 dose but will this mistake have an adverse outcome on the cycle? Should I have the scan earlier? What do you think is the best course of action?

    • I really could not say…without knowing details about your ovarian reserve.

      Geoff Sher

  5. Hi Dr Sher, my RE says high dose stims has a deleterious effect on egg quality. I know high dose stims can’t overstimulate a DOR ovary, but can it affect quality?

    • I respectfully disagree with your RE when it comes to DOR.

      Geoff Sher