Ask Our Doctors – Archive
Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Dear Doc,
Post FET cycle, my wife is six weeks pregnant and based on Beta HCG results we are expecting multiple pregnancies. My wife was on 8% Crinone (AM & PM) and 50 mg Gestone (PM) until now. As we are expecting multiple pregnancies my obstetrician and gynecologist has suggested that I UP the dose of 50 mg Gestone (PM) to 100 mg Gestone (PM) and keep the 8% Crinone (AM & PM) doses as it is.
My question is, will this “the more the better” advice have any adverse effects on the overall outcome? Can more progesterone have detrimental effects on the overall outcome? Please help.
Thanks,
– Tapish
I am not certain that more is better…but it probably won’t hurt.
Geoff Sher
Hi Dr Sher, we had an ER today and the eggs were of grade 1 (top) quality, but the sperm was borderline and worse than previous samples with progressive motility only at 10%. If the sperm parameters are bad does that mean that the overall quality of the sperms aren’t great? We did PICSI but because the parameters aren’t great does that reduce our chances overall? Would you recommend doing sperm DNA fragmentation tests? Many thanks in advance!
It it is too late to do a DFI now. Yes the chance of success will be slightly reduced, but pregnancy is still possible. You might consider doing PGS testing of the embryos at the blastocyst stage.
Geoff Sher
Hi, Dr. Sher. I found out after a single embryo transfer we’re expecting mono/di twins! We didn’t have pgs done on the embryo. My question is can an embryo be abnormal and still turn into identicals? Or does the embryo have to be normal to split? I’m so afraid of miscarriage as I’ve had many of them. But I am 9 weeks and both heartbeats were 171 and 172 which our RE said was great! Thanks for the time.
An abnormal embryo can also split!
Geoff Sher
Hi Doc,
Is in vitro fertilization an option for patients whom are Ureaplasma U. positive? At this point we have tried multiple antibiotics including the “last resort” moxifloxacin, but we have had no success. In your opinion is there enough evidence to dissuade couples with this diagnosis from attempting to have a child? Thank you.
No…there is not. It is a possible factor but its presence does NOT preclude successful implantation.
Geoff Sher
Hello doctor, I am 36 years old. My embryo transfer (2 blastocysts) was done on 5/20 & the first beta test done on 12th days was 272.9; however, the same test done 2days later shows only a slight increase of 324.9. Do you think this would be a viable pregnancy? This is our first cycle and we are very worried.
Hi,
Hopefully this is a quick question. With my first fresh cycle in 2014, it was successful and I have a beautiful girl. We’re now making number two – I have 4 frozen embryos. I’m on nasal spray bureseline and 3x2mg progynova from 2nd day of period. On day 6 I started bleeding, dark brown/black, it felt quite a bit that night and was quite watery. It has eased off and by day 12 is virtually gone. Tiny bit of spotting. Scan on day 11 shows lining at 6mm. I have a follow up scan on day 16 to check lining. If OK and bleeding all stopped then I will start progesterone, Clexane and steroids (for nk cells) with a transfer 5 days later. My question is, due to the bleeding should we just cancel the round, have a scratch and start again? Or if the spotting stops is there no reason to stop and we can proceed? Embryos are all blasts – 2x 6 day – 4ab, 4bb, and 2x 5 day 3bc, 3bc. I didn’t have a scratch this time or last time.
Thank you!
The bigger issue here is a pre-progesterone lining of 6mm, which in my opinion is not likely to result in a successful implantation. In fact I do not even undertake a transfer when the lining prior to progesterone or hCG is <8mm. Second, if you have NKa then in my opinion, Clexane and Steroids are insufficient. You need (in addition) intralipid administered at the right dosage and timing.
Good luck!
Geoff Sher