Our Medical Directors are outstanding physicians that you will find to be very personable and compassionate, who take care to ensure that you have the most cutting-edge fertility treatments at your disposal. This is your outlet to ask your questions to the doctors.
Hi Dr, Sher! I am about to start an ultrashort protocol (3 days of 0.1mg Decapeptyl followed by stims. Cetrotide to start on day 6 in a fixed regimen). I have also been prescribed Dexamethasone starting on the same day as decapeptyl. My questions are:
1. do you think it’s ok to use DEX in the protocol that i described above?
2. This is going to be a freeze cycle (I am having full testing done on the embies) for FET later. In this case, when and how do you suggest I stop DEX?
Thank you for time. This is a wonderful blog!
In my opinion, there is no advantage in using dexamethasone in a freeze-all cycle.
Geoff Sher
Dear Dr Sher,
I have had 2 missed mc (after having achieved pregnancy naturally relatively quickly). The first one the fetus measured 9 weeks when my body passed it at 12 weeks, and the second had no heartbeat when it measured 14 weeks. I was given misoprostol for the second mc to manage at home , the fetus came out quickly but the placenta took 3 days to come out. I didn’t know this was abnormal (is it?). Fast forward 4 years later I haven’t been able to get pregnant again, since laparoscopy confirmed I have clubbed fimbrae and partially blocked tubes.
Since my difficulties conceiving again only happened after the second mc (and it has all been w the same partener) and now I am putting all the pieces together/ thought back to the placenta issue, could you please tell me if a placenta taking 3 days to come out in a mc is abnormal and could have caused infection leading to my current condition? It’s odd bc I never had any infection symptoms at all, and a week after the mc the ultrasound showed no RPC.
It is possible that this led to endometritis that spread into the tubes and caused damage. The question is…did the endometritis also result in residual damage to the uterus and its lining???
Geoff Sher
I am 32 with a low amh of .31 I had IVF and it was a fresh and it failed my embryo was a 4AA. I did a FET and it resulted in a chemical I transferred 2 one a 6AB and one 4AA o was wondering does low SMH have anything to do with my egg quality
Hi I just wanted some advice I am 32 yrs old I just turned 32 and I have a AMH of .31 and I was told it was low for my age and I also have and I was on gonal f 300 n menopur 300 then later on centrotide I then went on to progesterone suppositories 2x a day and a progesterone pill and estrace both pills 3 times a day my levels were always great the doctor said i only made 6 eggs 2 died and 4 fertilized to 5 day blastocyst and fresh was a BFN and second was a BFP for a frozen 4aa and a 6ab but resulted in a chemical I didn’t get them pgs tested though and does low amh have anything to do with the quality of my eggs. Or is this some other issues I should be looking into
Dear Dr. Sher,
I am 41 years old and have been trying IVF for the last one year with 8 embryos across 4 cycles that came back with the following results:
On October 26, the special considerations embryo was transferred (FET) and I tested BFN yesterday.
What should I do next? Can I try to transfer one of the other embryos?
They are:
Mosaic Trisomy 3
Monosomy 16
44, XY, – 17, -22
Monosomy 16 (with a special note saying that the results were below the quality threshold and may result in a false positive. A rebiopsy may lead to different results).
I don’t see a way forward after 7 out of 8 embryos being abnormal at PGS and the one normal one did not implant. I am grateful for your help.
Mohini
I think both the mosaic and monosomic embryo could be transferred.
Geoff Sher